Ca⁺⁺Pure-HA is a hydroxyapatite resin used for the chromatographic separation of biomolecules. Its key applications include the purification of monoclonal and polyclonal antibodies, such as IgG, IgA, IgM, antibody fragments, fusion proteins, phosphoproteins, as well as the separation of single-stranded and double-stranded DNA.
Ca⁺⁺Pure-HA resin has been sintered at high temperatures to enhance its mechanical and pH stability, making it suitable for rigorous industrial-scale applications. At a 5-minute residence time, Ca⁺⁺Pure-HA has demonstrated a dynamic binding capacity (DBC) of 55 mg mAb/mg resin at 5% breakthrough.
Ca⁺⁺Pure-HA provides exceptional separation properties, unmatched selectivity, and high resolution for various classes of biomolecules. Its robust nature allows for the flexibility of using this resin at any stage of a process